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Protective effect of extract of Cordyceps sinensis in middle cerebral artery occlusion-induced focal cerebral ischemia in rats Behavioral and Brain Functions volume 6, article number: 61

When my dad was diagnosed with age related, cognitive decline, as a biologist, I knew there was something better than what you see on television. Cordyceps is the 2nd ingredient in the formula I developed for him (and I call it CO-GEN 10) coming to Green Valley in the fall.

Cordyceps serves several functions. Here is one such research abstract.

Abstract and Background

Ischemic hypoxic brain injury often causes irreversible brain damage. The lack of effective and widely applicable pharmacological treatments for ischemic stroke patients may explain a growing interest in traditional medicines. From the point of view of "self-medication" or "preventive medicine," Cordyceps sinensis was used in the prevention of cerebral ischemia in this paper.


The right middle cerebral artery occlusion model was used in the study. The effects of Cordyceps sinensis (Caterpillar fungus) extract on mortality rate, neurobehavior, grip strength, lactate dehydrogenase, glutathione content, Lipid Peroxidation, glutathione peroxidase activity, glutathione reductase activity, catalase activity, Na+K+ATPase activity and glutathione S transferase activity in a rat model were studied respectively.


Cordyceps sinensis extract significantly improved the outcome in rats after cerebral ischemia and reperfusion in terms of neurobehavioral function. At the same time, supplementation of Cordyceps sinensis extract significantly boosted the defense mechanism against cerebral ischemia by increasing antioxidants activity related to lesion pathogenesis. Restoration of the antioxidant homeostasis in the brain after reperfusion may have helped the brain recover from ischemic injury.


These experimental results suggest that complement Cordyceps sinensis extract is protective after cerebral ischemia... (More)


Prevention of early Alzheimer’s disease by erinacine A-enriched Hericium erinaceus mycelia pilot double-blind placebo-controlled study

When my father was diagnosed with cognitive decline, I developed an effective formula for him. Comprised of clinically established, plant ingredients that pharmaceutical companies won't promote, because no one can patent a natural plant. I call the formula CO-GEN 10. One ingredient in it is called Lions Mane (hericium erinaceus). Below is just one such trial on the cognition. Coming to Green Valley in the fall.

Frontiers in Aging Neuroscience 12, 155, 2020


To investigate the efficacy and safety of three H. erinaceus mycelia (EAHE) capsules (350 mg/capsule; containing 5 mg/g erinacine A active ingredient) per day for the treatment of patients with mild Alzheimer’s Disease (AD).


This study comprised a 3-week no-drug screening period, followed by a 49-week double-blind treatment period with 2-parallel groups in which eligible patients were randomized to either three 5 mg/g EAHE mycelia capsules per day or identical appearing placebo capsules. Cognitive assessments, ophthalmic examinations, biomarker collection, and neuroimaging were followed throughout the study period.


After 49 weeks of EAHE intervention, a significant decrease in Cognitive Abilities Screening Instrument score was noted in the placebo group, a significant improvement in Mini-Mental State Examination score was observed in the EAHE group and a significant Instrumental Activities of Daily Living score difference were found between the two groups. In addition, EAHE group achieved a significantly better contrast sensitivity when compared to the placebo group. Moreover, only the placebo group observed significantly lowered biomarkers such as calcium, albumin, apolipoprotein E4, hemoglobin, and brain-derived neurotrophic factor... (More)


Reader question: What are the best options for home health care in the area?

We're answering community questions from readers collected from our Community Conversation Survey!

Today’s question: "What are the options for finding the right home care to allow my father to stay in his home as long as possible?"

Answer: Wick Communications publishes an annual health services magazine called the “Green Valley Health Services Directory” that features a directory with many categories including home care. 

The section lists 24 agencies that provide home care assistance.

Head over to the Green Valley News and Sahuarita Sun office at 101 S. La Cañada Dr., Ste. 24 to pick up a free copy of the magazine!


#nursingassistantsweek #myhospice